ME:: Not tested on Humans yet but sounds promising go science go; September 2024:: Brigham and Women’s Hospital. PCANS Drug-free nasal spray blocks, neutralizes viruses, bacteria — Harvard Gazette
Discovered: Aug 31, 2025 19:05 (UTC)ME:: Not tested on Humans yet but sounds promising go science go; September 2024:: Brigham and Women’s Hospital. PCANS Drug-free nasal spray blocks, neutralizes viruses, bacteria — Harvard Gazette
- via @nwchapman’s toot and also there’s a an earlier drug free nasal spray using Iota-Carrageenan: see October 2021:: Efficacy of a Nasal Spray Containing Iota-Carrageenan in the Postexposure Prophylaxis of COVID-19 in Hospital Personnel Dedicated to Patients Care with COVID-19 Disease
QUOTE
- Read the whole thing: PCANS Drug-free nasal spray blocks, neutralizes viruses, bacteria — Harvard Gazette
Experiments in mice showed that a single dose of the PCANS nasal spray could effectively block infection from an influenza virus (PR8) at 25 times the lethal dose. Virus levels in the lungs were reduced by >99.99 percent, and the inflammatory cells and cytokines in the lungs of PCANS-treated animals were normal.
“The formulation’s ability to inactivate a broad spectrum of pathogens, including the deadly PR8 influenza virus, demonstrates its high effectiveness,” said co-senior author Yohannes Tesfaigzi, AstraZeneca Professor of Medicine in the Field of Respiratory and Inflammatory Diseases at BWH. “In a rigorous mouse model study, prophylactic treatment with PCANS demonstrated exceptional efficacy, with treated mice exhibiting complete protection, while the untreated group showed no such benefit.”
While the study’s limitations include the lack of human studies of PCANS, it provides a strong foundation for future research to explore the full potential of PCANS in a broader context. The researchers are exploring whether PCANS can also block allergens, opening a potential new avenue for allergy relief.